By stimulating the release of GH and insulin-like growth factor 1 (IGF-1), MK-677 helps increase protein synthesis, which is essential for building lean muscle mass. Users often report improved muscle fullness, increased strength, and enhanced workout performance when incorporating MK-677 into their fitness regimens.

FDA lists Ibutamoren as an ingredient that “… poses significant safety risks due to the potential for congestive heart failure in certain patients.” A clinical trial was stopped early due to concerns that Ibutamoren may increase the rate of heart failure. Ibutamoren is listed in the Australian Poisons Standard.

Ibutamoren ( INN Tooltip International Nonproprietary Name) (developmental code names MK-677, MK-0677, LUM-201, L-163,191; former tentative brand name Oratrope) is a potent, long-acting, orally-active, selective, and non-peptide agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth ...

Potential Side Effects of MK-677 Individuals who are vulnerable to insulin sensitivity or who have Diabetes may be at risk when taking MK-677. Symptoms associated with these conditions could possibly be exacerbated by the use of MK 677. As with any other compound, correct dosing and usage of MK-677 is the key.